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Article

Similar patterns of genomic alterations characterize primary mediastinal large-B-cell lymphoma and diffuse large-B-cell lymphoma.

Genes, chromosomes & cancer - 1 Feb 2002

Palanisamy Nallasivam, Abou-Elella Ashraf A, Chaganti Seeta R, Houldsworth Jane, Offit Kenneth, Louie Diane C, Terayu-Feldstein Julie, Cigudosa Juan C, Rao Pulivarthi H, Sanger Warren G, Weisenburger Dennis D, Chaganti R S K

Abstract excerpt

To address the possible genetic relationship between primary mediastinal large-B-cell lymphoma (PMLBCL) and diffuse large-B-cell lymphoma (DLBCL), we compared DNA copy number changes identified by comparative genomic hybridization (CGH) analysis of 40 PMLBCL and 91 DLBCL tumors. We assessed their karyotypes by G-banding; amplification of MYC, BCL2, and REL genes by Southern blotting; and incidence of...

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Share to Chromosome Banding
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, B-Cell

Share to Lymphoma, Large B-Cell, Diffuse

Share to Mediastinal Neoplasms

Share to Nucleic Acid Hybridization

Share to Proto-Oncogene Proteins c-bcl-6

Source

Identifiers

PMID: 11793437
DOI: 10.1002/gcc.10016

Genes

BCL6
BCL2
MYC
REL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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