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Article

Genetic toxicology assessment of HI-6 dichloride.

Environmental and molecular mutagenesis - 1 Jan 1996

Putman D, San R H, Bigger C A, Levine B S, Jacobson-Kram D

Abstract excerpt

The oxime HI-6 dichloride [1-(2 hydroxyiminomethyl -1-pyridino)-3-(4-carbamoyl-1-pyridino)-2-oxapropane dichloride monohydrate] has shown to be a potent reactivator of cholinesterase activity and may have efficacy for the treatment of organophosphate intoxication [SIPRI, 1976; Schenk et al.; Arch Toxicol 36:71-81, 1976]. As part of a preclinical safety assessment program, the genetic toxicology of HI-6 dichloride...

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Identifiers

PMID: 8603667
DOI: 10.1002/(SICI)1098-2280(1996)27:2<152::AID-EM9>3.0.CO;2-I

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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