Article
Genetic toxicology of acrylic acid.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jun 1992
McCarthy K L, Thomas W C, Aardema M J, Seymour J L, Putman D L, Yang L L, Curren R D, Valencia R
Abstract excerpt
Acrylic acid was tested for gene mutations in the in vitro CHO/HGPRT assay, for chromosome aberrations in CHO cells in culture, and for potential to induce unscheduled DNA synthesis in rat hepatocytes in culture. In vivo assays performed included the Drosophila sex-linked recessive lethal assay by both the feeding and injection routes, the in vivo cytogenetic assay in rat bone marrow cells after both a 1-day and...
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