Genetic toxicology of acrylic acid.

doi:10.1016/0278-6915(92)90102-q

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Article

Genetic toxicology of acrylic acid.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jun 1992

McCarthy K L, Thomas W C, Aardema M J, Seymour J L, Putman D L, Yang L L, Curren R D, Valencia R

Abstract excerpt

Acrylic acid was tested for gene mutations in the in vitro CHO/HGPRT assay, for chromosome aberrations in CHO cells in culture, and for potential to induce unscheduled DNA synthesis in rat hepatocytes in culture. In vivo assays performed included the Drosophila sex-linked recessive lethal assay b...

Topics

Acrylates
Animals
Body Weight
Bone Marrow
Bone Marrow Cells
CHO Cells
Cells, Cultured
Chromosome Aberrations
Cricetinae
DNA Damage
Drosophila
Female
Hydrogen-Ion Concentration
Liver
Male
Mice
Mutagenicity Tests
Mutagens

Source

Open in PubMed

Identifiers

PMID: 1500036
DOI: 10.1016/0278-6915(92)90102-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1500036-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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