Article
The genetic toxicology of Gene-Tox non-carcinogens.
Mutation research - 1 Jan 2000
Waters M D, Bergman H B, Nesnow S
Abstract excerpt
The Gene-Tox Program has identified 61 chemicals that have been tested in chronic rodent carcinogenesis bioassays and found to be inactive. The genetic toxicology data of these 61 non-carcinogens is reviewed and summarized. A large proportion of these chemicals have been tested to a limited extent in genetic toxicity bioassays: 32 in 2 tests or less. Of the remaining 29 chemicals, 28% have been tested in 9 or...
Topics
- Animals
- Biological Assay
- Carcinogens
- Chromosome Aberrations
- DNA Damage
- Information Systems
- Mutagenicity Tests
- Mutation