Article
Characterization and comparison of the lytic function of NKR-P1+ and NKR-P1-rat natural killer cell clones established from NKR-P1bright/TCR alpha beta-cell lines.
Natural immunity - 1 Jan 1995
Brissette-Storkus C, Appasamy P M, Hayes L A, Kaufman C L, Ildstad S T, Chambers W H
Abstract excerpt
From sorted rat NKR-P1bright/T cell receptor (TCR) alpha beta-cells, we established interleukin (IL)-2-dependent cell lines with the morphology, phenotype and function of natural killer (NK) cells. The cell lines NKbr11.3 and NKbr1.28 had large-granular-lymphocyte morphology, were capable of lysi...
Topics
- Animals
- Antibody-Dependent Cell Cytotoxicity
- Antigens, Surface
- Blotting, Northern
- Cell Culture Techniques
- Cell Line
- Clone Cells
- Cytotoxicity, Immunologic
- Killer Cells, Natural
- Lectins, C-Type
- Mice
- Mice, Inbred C57BL
- NK Cell Lectin-Like Receptor Subfamily B
- Phenotype
- Rats
- Rats, Inbred F344
- Tumor Cells, Cultured