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Article

Influence of NK cell magnetic bead isolation methods on phenotype and function of murine NK cells.

Journal of immunological methods - 30 Apr 2012

Meinhardt Kathrin, Kroeger Irena, Abendroth Alexandra, Müller Sabine, Mackensen Andreas, Ullrich Evelyn

Abstract excerpt

Natural killer (NK) cells are a promising tool for cell therapy due to their capacity to lyse tumor cells without prior activation and their influence on the innate as well as the adaptive immunity. To characterize distinct NK cell populations, it is important to find a reliable isolation method. We investigated separation methods for NK cell isolation by magnetic bead labeling. There are three commonly used...

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PMID: 22306357
DOI: 10.1016/j.jim.2012.01.008

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