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Article

Genetic basis of maturity-onset diabetes of the young.

Endocrinology and metabolism clinics of North America - 1 Jun 2006

Vaxillaire Martine, Froguel Philippe

Abstract excerpt

Most valuable breakthroughs in the genetics of type 2 diabetes mellitus have arisen from familial linkage analysis of maturity-onset diabetes of the young, an autosomal dominant form of diabetes typically occurring before 25 years of age and caused by primary insulin-secretion defects. Despite its low prevalence, MODY is not a single entity but presents genetic, metabolic, and clinical heterogeneity. MODY can...

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PMID: 16632099
DOI: 10.1016/j.ecl.2006.02.009

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