Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.

doi:10.1056/NEJM199303113281005

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Article

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.

The New England journal of medicine - 11 Mar 1993

Froguel P, Zouali H, Vionnet N, Velho G, Vaxillaire M, Sun F, Lesage S, Stoffel M, Takeda J, Passa P

Abstract excerpt

BACKGROUND AND METHODS: Non-insulin-dependent diabetes mellitus (NIDDM) is a genetically heterogeneous disorder. Maturity-onset diabetes of the young, a form of NIDDM with an early age of onset and autosomal dominant inheritance, can result from mutations in glucokinase, a key enzyme of glucose m...

Topics

Adult
Age Factors
Base Sequence
Blood Glucose
Child
DNA
Diabetes Mellitus, Type 2
Exons
Female
Genetic Linkage
Glucokinase
Glucose Tolerance Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hyperglycemia

Infant

Male

Middle Aged

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 8433729
DOI: 10.1056/NEJM199303113281005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8433729-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.PMID 8433729Read ↗

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