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Article

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.

The New England journal of medicine - 11 Mar 1993

Froguel P, Zouali H, Vionnet N, Velho G, Vaxillaire M, Sun F, Lesage S, Stoffel M, Takeda J, Passa P

Abstract excerpt

BACKGROUND AND METHODS: Non-insulin-dependent diabetes mellitus (NIDDM) is a genetically heterogeneous disorder. Maturity-onset diabetes of the young, a form of NIDDM with an early age of onset and autosomal dominant inheritance, can result from mutations in glucokinase, a key enzyme of glucose metabolism in beta cells and the liver. We studied 32 French families with maturity-onset diabetes of the young as well...

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PMID: 8433729
DOI: 10.1056/NEJM199303113281005

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Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.PMID 8433729Read ↗

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[Diabetes mellitus caused by a mutation of glucokinase gene. Report of an affected family].Semantic proximity Read ↗

[A three-year follow-up observation of a pedigree of maturity onset diabetes of the young caused by a novel mutation of glucokinase and literature review].Semantic proximity Read ↗

A novel heterozygous mutation in the glucokinase gene is responsible for an early-onset mild form of maturity-onset diabetes of the young, type 2.Semantic proximity Read ↗

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Genetic and clinical characteristics of Chinese children with Glucokinase-maturity-onset diabetes of the young (GCK-MODY).Semantic proximity Read ↗

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia.Semantic proximity Read ↗

Maturity-Onset Diabetes of the Young (MODY): Genetic and Clinical CharacteristicsSemantic proximity Read ↗

Maturity-onset diabetes of the young.Semantic proximity Read ↗

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