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Article

Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes.

Endocrine reviews - 1 May 2008

Vaxillaire Martine, Froguel Philippe

Abstract excerpt

Most valuable breakthroughs in the genetics of type 2 diabetes for the past two decades have arisen from candidate gene studies and familial linkage analysis of maturity-onset diabetes of the young (MODY), an autosomal dominant form of diabetes typically occurring before 25 years of age caused by primary insulin secretion defects. Despite its low prevalence, MODY is not a single entity but presents genetic,...

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Identifiers

PMID: 18436708
DOI: 10.1210/er.2007-0024

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