Article
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds.
Nature genetics - 1 Mar 1996
Tavtigian S V, Simard J, Rommens J, Couch F, Shattuck-Eidens D, Neuhausen S, Merajver S, Thorlacius S, Offit K, Stoppa-Lyonnet D, Belanger C, Bell R, Berry S, Bogden R, Chen Q, Davis T, Dumont M, Frye C, Hattier T, Jammulapati S, Janecki T, Jiang P, Kehrer R, Leblanc J F, Mitchell J T, McArthur-Morrison J, Nguyen K, Peng Y, Samson C, Schroeder M, Snyder S C, Steele L, Stringfellow M, Stroup C, Swedlund B, Swense J, Teng D, Thomas A, Tran T, Tranchant M, Weaver-Feldhaus J, Wong A K, Shizuya H, Eyfjord J E, Cannon-Albright L, Tranchant M, Labrie F, Skolnick M H, Weber B, Kamb A, Goldgar D E
Abstract excerpt
Breast carcinoma is the most common malignancy among women in developed countries. Because family history remains the strongest single predictor of breast cancer risk, attention has focused on the role of highly penetrant, dominantly inherited genes in cancer-prone kindreds (1). BRCA1 was localiz...
Topics
- BRCA2 Protein
- Base Sequence
- Breast Neoplasms, Male
- Cell Line
- Chromosomes, Human, Pair 13
- Cloning, Molecular
- DNA Primers
- Exons