Article
Natural resistance to infection with Legionella pneumophila: chromosomal localization of the Lgn1 susceptibility gene.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 1995
Beckers M C, Yoshida S, Morgan K, Skamene E, Gros P
Abstract excerpt
Legionella pneumophila is a strict intracellular pathogen that replicates in the professional phagocytes of the human and guinea pig host. Although murine macrophages from most inbred strains are non-permissive to intracellular replication of L. pneumophila, inflammatory macrophages from the mous...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Genetic Predisposition to Disease
- Humans
- Legionella pneumophila
- Legionnaires' Disease
- Macrophages, Peritoneal
- Mice
- Mice, Inbred C57BL
