Article
Genetic control of natural resistance in mouse macrophages regulating intracellular Legionella pneumophila multiplication in vitro.
Infection and immunity - 1 Jan 1991
Yoshida S, Goto Y, Mizuguchi Y, Nomoto K, Skamene E
Abstract excerpt
It is known that Legionella pneumophila proliferates in peritoneal macrophage cultures derived from A/J mice but not in macrophage cultures derived from many other strains, including C57BL/6 mice. To analyze the genetic control of this trait and the location of the Legionella resistance-susceptibility gene, we prepared segregating progeny of A/J and C57BL/6 mice and determined the levels of susceptibility of...
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