Genetic control of natural resistance in mouse macrophages regulating intracellular Legionella pneumophila multiplication in vitro.

doi:10.1128/iai.59.1.428-432.1991

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Article

Genetic control of natural resistance in mouse macrophages regulating intracellular Legionella pneumophila multiplication in vitro.

Infection and immunity - 1 Jan 1991

Yoshida S, Goto Y, Mizuguchi Y, Nomoto K, Skamene E

Abstract excerpt

It is known that Legionella pneumophila proliferates in peritoneal macrophage cultures derived from A/J mice but not in macrophage cultures derived from many other strains, including C57BL/6 mice. To analyze the genetic control of this trait and the location of the Legionella resistance-susceptib...

Topics

Alleles
Animals
Female
Immunity, Innate
In Vitro Techniques
Legionella
Legionellosis
Macrophages
Male
Mice
Mice, Inbred Strains
Species Specificity

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