Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic mutations at CA-repeat loci.

Human mutation - 1 Jan 1992

Jones M H, Nakamura Y

Abstract excerpt

We found somatic mutations, detected as novel PCR bands, at three separate polymorphic CA-repeat loci. At one of these loci, analyzed in a three-generation pedigree, a new band generated from the same paternal allele was observed in four of six offspring. The other two children inherited the alternative paternal allele unchanged. Somatic mutations at two additional loci were identified upon subsequent comparison...

Topics

Alleles
Base Sequence
DNA Mutational Analysis
DNA, Neoplasm
DNA, Satellite
Female
Gene Frequency
Genetic Markers
Genital Neoplasms, Female
Humans
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Pedigree

Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 1301929
DOI: 10.1002/humu.1380010309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1301929-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic mutations at CA-repeat loci.PMID 1301929Read ↗

Evaluation of allelic alterations in short tandem repeats in different kinds of solid tumors--possible pitfalls in forensic casework.Semantic proximity Read ↗

Genotypic analysis of multiple loci in somatic cells by whole genome amplification.Semantic proximity Read ↗

Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs.Semantic proximity Read ↗

A simple approach for classifying new mutations as somatic or germinal in DNA samples lacking paired tissue.Semantic proximity Read ↗

Spontaneous length variation in microsatellite DNA from human T-cell clones.Semantic proximity Read ↗

Evaluation of gastrointestinal cancer tissues as a source of genetic information for forensic investigations by using STRs.Semantic proximity Read ↗

New alleles at microsatellite loci in CEPH families mainly arise from somatic mutations in the lymphoblastoid cell lines.Semantic proximity Read ↗

A hereditary genetic marker closely associated with microsatellite instability in lung cancer.Semantic proximity Read ↗

In vivo somatic microsatellite mutations identified in non-malignant human tissue.Semantic proximity Read ↗

Experimentally observed germline mutations at human micro- and minisatellite loci.Semantic proximity Read ↗

Allele non-amplification: a source of confusion in linkage studies employing microsatellite polymorphisms.Semantic proximity Read ↗

Hypermutability at a poly(A/T) tract in the human germline.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.