Article
Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature.
Genes, chromosomes & cancer - 1 Apr 2011
Galindo Cristi L, McIver Lauren J, Tae Hongseok, McCormick John F, Skinner Michael A, Hoeschele Ina, Lewis Cheryl M, Minna John D, Boothman David A, Garner Harold R
Abstract excerpt
Using a custom CGH-like oligonucleotide array to measure the global microsatellite content in the genomes of 72 cancer, cancer-free, and high risk patient and cell line samples (56 germline DNA and 16 in tumor or tumor cell line DNA) we found a unique, reproducible, and statistically significant pattern of 18 motif-specific microsatellite families (out of 962 possible 1-6 mer repeats) in breast cancer patient...
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