Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway.

Journal of cell science - 1 Nov 1995

Singer-Krüger B, Stenmark H, Zerial M

Abstract excerpt

Ypt51p, a small GTPase of Saccharomyces cerevisiae, has been previously identified as a structural homolog of mammalian Rab5. Although disruption analysis revealed that the protein is required for endocytic transport and for vacuolar protein sorting, the precise step controlled by Ypt51p was not determined. In this work we show that by heterologous expression in animal cells Ypt51p was targeted to Rab5-positive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Biological Transport
Share to Cricetinae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Phenotype

Share to Proteins

Share to Saccharomyces cerevisiae

Source

Identifiers

PMID: 8586662
DOI: 10.1242/jcs.108.11.3509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway.PMID 8586662Read ↗

Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast.Semantic proximity Read ↗

Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast.Semantic proximity Read ↗

Yeast Ysl2p, homologous to Sec7 domain guanine nucleotide exchange factors, functions in endocytosis and maintenance of vacuole integrity and interacts with the Arf-Like small GTPase Arl1p.Semantic proximity Read ↗

Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway.Semantic proximity Read ↗

Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function.Semantic proximity Read ↗

The Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway.Semantic proximity Read ↗

Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity.Semantic proximity Read ↗

Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.Semantic proximity Read ↗

Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartments.Semantic proximity Read ↗

The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance.Semantic proximity Read ↗

Genetic and functional interaction between Ryh1 and Ypt3: two Rab GTPases that function in S. pombe secretory pathway.Semantic proximity Read ↗

Identification of regulators for Ypt1 GTPase nucleotide cycling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.