Article
Analysis of genetic polymorphism of deoxyribonuclease I in Ovambo and Turk populations using a genotyping method.
Biochemical genetics - 1 Dec 2005
Fujihara Junko, Hieda Yoko, Takayama Koji, Xue Yuying, Nakagami Norihito, Imamura Shinji, Kataoka Kaori, Takeshita Haruo
Abstract excerpt
Deoxyribonuclease I (DNase I) polymorphism has been used as a valuable marker in genetic and clinical investigations. Six codominant alleles are known for DNase I, DNASE1*1, *2, *3, *4, and the recently discovered alleles *5 and *6. To detect these two new alleles, we added a new DNase I genotyping method based on both an allele-specific amplification and mismatched polymerase chain reaction (PCR). These methods...
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