Article
Factor V Leiden: an additional risk factor for thrombosis in protein S deficient families?
Thrombosis and haemostasis - 1 Aug 1995
Koeleman B P, van Rumpt D, Hamulyák K, Reitsma P H, Bertina R M
Abstract excerpt
We recently reported a high prevalence of the FV Leiden mutation (R506Q, responsible for Activated Protein C resistance) among symptomatic protein C deficient probands (19%), and the involvement of the FV Leiden mutation in the expression of thrombophilia in six protein C deficient families. Here...
Topics
- Adolescent
- Adult
- Age of Onset
- Child
- Factor V
- Factor V Deficiency
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Pedigree
- Prevalence
- Protein S Deficiency
- Risk Factors
- Thrombosis