Article
Factor V Leiden: an additional risk factor for thrombosis in protein S deficient families?
Thrombosis and haemostasis - 1 Aug 1995
Koeleman B P, van Rumpt D, Hamulyák K, Reitsma P H, Bertina R M
Abstract excerpt
We recently reported a high prevalence of the FV Leiden mutation (R506Q, responsible for Activated Protein C resistance) among symptomatic protein C deficient probands (19%), and the involvement of the FV Leiden mutation in the expression of thrombophilia in six protein C deficient families. Here, we report the results of a similar study in protein S deficient probands and families. Among 16 symptomatic protein S...
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