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Article

Genetic analysis, phenotypic diagnosis, and risk of venous thrombosis in families with inherited deficiencies of protein S.

Blood - 15 Mar 2000

Makris M, Leach M, Beauchamp N J, Daly M E, Cooper P C, Hampton K K, Bayliss P, Peake I R, Miller G J, Preston F E

Abstract excerpt

Protein S deficiency is a recognized risk factor for venous thrombosis. Of all the inherited thrombophilic conditions, it remains the most difficult to diagnose because of phenotypic variability, which can lead to inconclusive results. We have overcome this problem by studying a cohort of patients from a single center where the diagnosis was confirmed at the genetic level. Twenty-eight index patients with protein...

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Source

Identifiers

PMID: 10706858

Genes

PROS1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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