Article
Suppressing effect of WR-2721 on micronuclei induced by cyclophosphamide in mice.
Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1995
Czyzewska A, Mazur L
Abstract excerpt
The effect of WR-2721 against cyclophosphamide-induced clastogenicity was studied using the in vivo micronucleus assay. The frequency of micronuclei in polychromatic erythrocytes in the peripheral blood of mice treated with WR-2721 and cyclophosphamide (CP), each of the compounds at a dose of 200 mg/kg body weight, was evaluated during the 15-day period. The suppressing effect of WR-2721, given 30 min prior to...
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