Suppressing effect of WR-2721 on micronuclei induced by cyclophosphamide in mice.

doi:10.1002/tcm.1770150303

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Article

Suppressing effect of WR-2721 on micronuclei induced by cyclophosphamide in mice.

Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1995

Czyzewska A, Mazur L

Abstract excerpt

The effect of WR-2721 against cyclophosphamide-induced clastogenicity was studied using the in vivo micronucleus assay. The frequency of micronuclei in polychromatic erythrocytes in the peripheral blood of mice treated with WR-2721 and cyclophosphamide (CP), each of the compounds at a dose of 200...

Topics

Amifostine
Animals
Cyclophosphamide
Erythrocytes
Male
Mice
Micronuclei, Chromosome-Defective
Micronucleus Tests
Mutagens
Mutation

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