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Article

Anticlastogenic activity of beta-carotene against cyclophosphamide in mice in vivo.

Mutation research - 1 May 1991

Mukherjee A, Agarwal K, Aguilar M A, Sharma A

Abstract excerpt

beta-Carotene (BC), a natural food colourant and an antioxidant, acts as an antimutagen/anticarcinogen in several test systems. The anticlastogenic activity of BC against cyclophosphamide (CP) was studied in bone marrow cells of mice in vivo. Seven days' oral priming with BC (2.7 and 27 mg/kg b.w.) followed by an acute treatment with cyclophosphamide (25 mg/kg b.w.; i.p.) inhibited clastogenicity. The values of...

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Identifiers

PMID: 2034238
DOI: 10.1016/0165-7992(91)90032-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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