Anticlastogenic activity of beta-carotene against cyclophosphamide in mice in vivo.

doi:10.1016/0165-7992(91)90032-y

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Article

Anticlastogenic activity of beta-carotene against cyclophosphamide in mice in vivo.

Mutation research - 1 May 1991

Mukherjee A, Agarwal K, Aguilar M A, Sharma A

Abstract excerpt

beta-Carotene (BC), a natural food colourant and an antioxidant, acts as an antimutagen/anticarcinogen in several test systems. The anticlastogenic activity of BC against cyclophosphamide (CP) was studied in bone marrow cells of mice in vivo. Seven days' oral priming with BC (2.7 and 27 mg/kg b.w...

Topics

Animals
Carotenoids
Chromosome Aberrations
Cyclophosphamide
Male
Mice
Micronucleus Tests
Mutation
beta Carotene

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