Article
Role of chlorophyllin as an in vivo anticlastogen: protection against gamma-radiation and chemical clastogens.
Mutation research - 1 Sept 1994
Abraham S K, Sarma L, Kesavan P C
Abstract excerpt
Chlorophyllin was evaluated in the mouse bone marrow micronucleus test for its possible protective effects against chromosomal damage induced by gamma-radiation, cyclophosphamide, N-nitroso-N-ethylurea and urethane. Three doses of chlorophyllin (50, 100 and 200 mg/kg, b.w.) were orally administered to mice 2 h before exposure to the clastogens under investigation. The results obtained demonstrated that...
Topics
- Animals
- Antimutagenic Agents
- Chlorophyllides
- Gamma Rays
- Male
- Mice
- Micronucleus Tests
- Mutation
- Radiation Injuries, Experimental