Article
Alterations in the p'R promoter of coliphage lambda modify both its activity and interaction with the integration host factor (IHF).
Molecular & general genetics : MGG - 1 May 1990
Kur J, Hasan N, Szybalski W
Abstract excerpt
A limited number of deletion/insertions and a point mutation in the -35 region of the p'R promoter of phage lambda were examined and found to influence both transcription and its repression by the integration host factor (IHF). Positive effects on transcription (in the absence of IHF) are small (...
Topics
- Bacterial Proteins
- Bacteriophage lambda
- Base Sequence
- DNA-Binding Proteins
- Integration Host Factors
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Plasmids
- Promoter Regions, Genetic
- Transcription, Genetic