Article
Inhibitors of ADP-ribosylation suppress phenotypic modulation and proliferation of smooth muscle cells cultured from rat aorta.
Differentiation; research in biological diversity - 1 Nov 1995
Thyberg J, Hultgårdh-Nilsson A, Kallin B
Abstract excerpt
The effects of hexamethylenebisacetamide (HMBA), an inhibitor of poly-ADP-ribosylation, and meta-iodobenzylguanidine (MIBG), an inhibitor of mono-ADP-ribosylation, on the phenotypic properties and proliferation of cultured rat aortic smooth muscle cells were studied using a combination of structu...
Topics
- 3-Iodobenzylguanidine
- ADP Ribose Transferases
- Acetamides
- Animals
- Aorta
- Biomarkers
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Enzyme Inhibitors
- Iodobenzenes
- Male
- Muscle Proteins
- Muscle, Smooth, Vascular
- Phenotype
- Poly(ADP-ribose) Polymerase Inhibitors
- RNA, Messenger
- Rats