Article
Phenotype-specific inhibition of the vascular smooth muscle cell cycle by high glucose treatment.
Diabetologia - 1 Apr 2007
Zheng X-L, Yuan S-G, Peng D-Q
Abstract excerpt
AIMS/HYPOTHESIS: Diabetes accelerates the development of atherosclerosis, which critically involves the proliferation of vascular smooth muscle cells (SMCs). However, how high glucose treatment regulates SMC proliferation is controversial. Considering the established SMC heterogeneity, we hypothesised that glucose treatment may have distinct effects on proliferation of the various phenotypic SMCs. MATERIALS AND...
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