Article
Associations of HLA-DRB and -DQB genes with two and five year outcome in rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Jan 1996
Eberhardt K, Fex E, Johnson U, Wollheim F A
Abstract excerpt
OBJECTIVE: To evaluate the clinical usefulness of genomic HLA typing during the first five years of established rheumatoid arthritis (RA). METHODS: The HLA-DRB and -DQB alleles were determined by restriction length polymorphisms and polymerase chain reaction amplification with sequence specific p...
Topics
- Adult
- Aged
- Alleles
- Arthritis, Rheumatoid
- Female
- Follow-Up Studies
- Genes, MHC Class II
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Testing
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length