Article
HLA markers and prediction of clinical course and outcome in rheumatoid arthritis.
Arthritis and rheumatism - 1 Feb 1997
Wagner U, Kaltenhäuser S, Sauer H, Arnold S, Seidel W, Häntzschel H, Kalden J R, Wassmuth R
Abstract excerpt
OBJECTIVE: To evaluate HLA markers as early prognostic factors for disease severity in rheumatoid arthritis (RA). METHODS: HLA genotyping was carried out in a retrospective analysis of 66 RA patients and in a prospective study of 55 RA patients and 87 healthy controls using polymerase chain reaction-based methods for HLA-DRB1 specificities, DR4 alleles, and their linked DQB1 alleles, as well as HLA-B27. The...
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