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Article

Prospective analysis of the impact of HLA-DR and -DQ on joint destruction in recent-onset rheumatoid arthritis.

Rheumatology (Oxford, England) - 1 Apr 2003

Wagner U, Kaltenhäuser S, Pierer M, Seidel W, Tröltzsch M, Häntzschel H, Kalden J R, Wassmuth R

Abstract excerpt

OBJECTIVE: To evaluate the differential impact of HLA-DR and -DQ on the progression of erosive disease in the clinical course of early rheumatoid arthritis (RA). METHODS: HLA genotyping for HLA-DR and -DQ was carried out in a prospective study of 87 patients with early RA. The progression of erosive disease was assessed by radiological scores over a period of 2 yr in all patients and over 4 yr in 77 patients. The...

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PMID: 12649403
DOI: 10.1093/rheumatology/keg190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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