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Article

Epitope tagging permits cell surface detection of functional CFTR.

The American journal of physiology - 1 Dec 1995

Howard M, DuVall M D, Devor D C, Dong J Y, Henze K, Frizzell R A

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is a phosphorylation-activated Cl channel responsible for adenosine 3',5'-cyclic monophosphate (cAMP)-induced Cl secretion across the apical membranes of epithelial cells. To optimize its detection for membrane localization studies, we tagged CFTR with epitope sequences at the carboxy terminus or in the fourth external loop. When epitopes were added...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8572187
DOI: 10.1152/ajpcell.1995.269.6.C1565

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Epitope tagging permits cell surface detection of functional CFTR.PMID 8572187Read ↗

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