Article
Heterogeneity between men and women in the influence of the HLA-DRB1 shared epitope on the clinical expression of rheumatoid arthritis.
Arthritis and rheumatism - 1 Jun 2002
del Rincón Inmaculada, Battafarano Daniel F, Arroyo Ramón A, Murphy Frederick T, Escalante Agustín
Abstract excerpt
OBJECTIVE: To test the hypothesis that the influence of the HLA-DRB1 shared epitope (SE) on the clinical manifestations of rheumatoid arthritis (RA) differs between men and women. METHODS: We assessed 777 consecutive RA patients for age at disease onset, articular manifestations, subcutaneous nodules, laboratory and radiographic findings, and treatment received. We typed HLA-DRB1 alleles by polymerase chain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
