Article
Involvement of Ras/Raf/AP-1 in BMP-4 signaling during Xenopus embryonic development.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jan 1996
Xu R H, Dong Z, Maeno M, Kim J, Suzuki A, Ueno N, Sredni D, Colburn N H, Kung H F
Abstract excerpt
Previously, we elucidated the role of bone morphogenetic protein 4 (BMP-4) in the dorsal-ventral patterning of the Xenopus embryo by using a dominant negative mutant of the BMP-4 receptor (DN-BR). The present paper describes the involvement of Ras, Raf, and activator protein 1 (AP-1) in BMP-4 signaling during Xenopus embryonic development. The AP-1 activity was determined by injecting an AP-1-dependent luciferase...
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