Article
Heparan sulfate stimulates extracellular matrix protein synthesis by mesangial cells in culture.
Nephron - 1 Jan 1995
Groggel G C, Hughes M L
Abstract excerpt
Heparan sulfate, a glycosaminoglycan which is a component of the glomerular basement membrane and the mesangial matrix, has been demonstrated to inhibit mesangial cell growth. The present studies investigated the effects of heparan sulfate on extracellular matrix protein synthesis by cultured rat mesangial cells. Mesangial cells were metabolically labeled with 35S-methionine and specific extracellular matrix...
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