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Human CD4<sup>+</sup> T cells stimulated by conserved adenovirus 5 hexon peptides recognize cells infected with different species of human adenovirus

25 Aug 2006

Abstract excerpt

The immune response against human adenovirus (HAdV) has gained interest because of the application of HAdV-based vectors in gene therapy and the high incidence of infections in pediatric recipients of allogeneic stem cell grafts. Because antiviral medication is frequently ineffective, the option of adoptive transfer of HAdV-specific donor-derived T cells in these immunocompromised patients is investigated. To...

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PMID: 16933360
DOI: 10.1002/eji.200535786

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