Article
The Drosophila wings apart gene anchors a novel, evolutionarily conserved pathway of neuromuscular development.
Genetics - 1 Nov 2013
Morriss Ginny R, Jaramillo Carmelita T, Mikolajczak Crystal M, Duong Sandy, Jaramillo Maryann S, Cripps Richard M
Abstract excerpt
wings apart (wap) is a recessive, semilethal gene located on the X chromosome in Drosophila melanogaster, which is required for normal wing-vein patterning. We show that the wap mutation also results in loss of the adult jump muscle. We use complementation mapping and gene-specific RNA interference to localize the wap locus to the proximal X chromosome. We identify the annotated gene CG14614 as the gene affected...
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