Article
Notch pathway repression by vestigial is required to promote indirect flight muscle differentiation in Drosophila melanogaster.
Developmental biology - 1 Jul 2006
Bernard F, Dutriaux A, Silber J, Lalouette A
Abstract excerpt
Drosophila dorsal longitudinal muscles develop during metamorphosis by fusion of myoblasts with larval templates. It has been shown that both vestigial and Notch are crucial for correct formation of these muscles. We investigated the relationship between vestigial and the Notch pathway during this process. Using Enhancer of Split Region Transcript m6 gene expression as a reporter of Notch pathway activity, we...
Topics
- Animals
- Calcium-Binding Proteins
- Cell Differentiation
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- Intercellular Signaling Peptides and Proteins
- Jagged-1 Protein
- Membrane Proteins
- Muscle Fibers, Skeletal
- Muscles
- Mutation
- Myoblasts
