Article
The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer.
G3 (Bethesda, Md.) - 2 Apr 2015
Bieli Dimitri, Kanca Oguz, Gohl Daryl, Denes Alexandru, Schedl Paul, Affolter Markus, Müller Martin
Abstract excerpt
The selector gene apterous (ap) plays a key role during the development of the Drosophila melanogaster wing because it governs the establishment of the dorsal-ventral (D-V) compartment boundary. The D-V compartment boundary is known to serve as an important signaling center that is essential for the growth of the wing. The role of Ap and its downstream effectors have been studied extensively. However, very little...
Topics
- Animals
- Drosophila Proteins
- Drosophila melanogaster
- Enhancer Elements, Genetic
- Gene Expression Regulation
- Genes, Dominant
- Genes, Reporter
- Genetic Loci
- Integrases
- LIM-Homeodomain Proteins
- Mutagenesis, Insertional
- Mutation
- Penetrance