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Article

Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 1995

Mullick A, Groulx N, Trasler D, Gros P

Abstract excerpt

Looptail (Lp) is a mutation on the distal portion of mouse Chromosome (Chr) 1 that affects neurulation in mouse and is phenotypically expressed by appearance of an open neural tube along the entire antero-posterior axis of the embryo (craniorachischisis). Nhlh1, a member of the basic helix-loop-helix family of transcription factors, is expressed in the developing neural tube in structures affected by the Lp...

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PMID: 8563167
DOI: 10.1007/BF00354291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nhlh1, a basic helix-loop-helix transcription factor, is very tightly linked to the mouse looptail (Lp) mutation.PMID 8563167Read ↗

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Identification of the mouse Loop-tail gene: a model for human craniorachischisis?Semantic proximity Read ↗

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