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Article

Mutational analysis of the CDKN2 gene in metastases from patients with cutaneous malignant melanoma.

British journal of cancer - 1 Feb 1996

Platz A, Ringborg U, Lagerlöf B, Lundqvist E, Sevigny P, Inganäs M

Abstract excerpt

We analysed 26 metastases from 25 patients with sporadic cutaneous malignant melanoma for alterations in the CDKN2 gene by a combined polymerase chain reaction/single-strand conformation polymorphism (PCR/SSCP)/nucleotide sequencing approach. Eleven alterations (one in exon 1, five in exon 2 and five in the 3' non-coding sequence of the exon 3 region) were concordantly and independently detected by both SSCP and...

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Open in PubMed Open full text

Identifiers

PMID: 8562340
DOI: 10.1038/bjc.1996.59
PMCID: PMC2074427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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