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Article

Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype.

Pharmacogenetics - 1 Apr 2001

Ramachandran S, Fryer A A, Smith A G, Lear J T, Bowers B, Hartland A J, Whiteside J R, Jones P W, Strange R C

Abstract excerpt

Previous studies have shown that patients who present at first or a later presentation with a cluster of new basal cell carcinoma (BCC) comprise a subgroup, termed multiple presentation phenotype (MPP), that is at increased risk of developing further lesions. In this study, we examined the hypothesis that patients who develop multiple clusters are a high-risk subgroup. We found, in a total group of 926 BCC...

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Topics

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Share to Carcinoma, Basal Cell
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Calcitriol

Share to Risk Factors

Share to Skin Neoplasms

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 11337940
DOI: 10.1097/00008571-200104000-00008

Genes

GSTT1
TNF
VDR
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype.PMID 11337940Read ↗

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Basal cell carcinoma.Semantic proximity Read ↗

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Multiple cutaneous basal cell carcinomas: glutathione S-transferase (GSTM1, GSTT1) and cytochrome P450 (CYP2D6, CYP1A1) polymorphisms influence tumour numbers and accrual.Semantic proximity Read ↗

Susceptibility to multiple cutaneous basal cell carcinomas: significant interactions between glutathione S-transferase GSTM1 genotypes, skin type and male gender.Semantic proximity Read ↗

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