Article
Mutations within the 5' nontranslated RNA of cell culture-adapted hepatitis A virus which enhance cap-independent translation in cultured African green monkey kidney cells.
Journal of virology - 1 Feb 1996
Schultz D E, Honda M, Whetter L E, McKnight K L, Lemon S M
Abstract excerpt
Mutations in the 5' nontranslated RNA (5'NTR) of an attenuated, cell culture-adapted hepatitis A virus (HAV), HM175/P16, enhance growth in cultured African green monkey kidney (BS-C-1) cells but not in fetal rhesus monkey kidney (FRhK-4) cells (S. P. Day, P. Murphy, E. A. Brown, and S. M. Lemon,...
Topics
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- Chlorocebus aethiops
- DNA, Viral
- DNA-Directed RNA Polymerases
- Gene Expression Regulation, Viral
- Hepatovirus
- Humans
- Liver
- Macaca mulatta
- Molecular Sequence Data
- Mutation
- Protein Biosynthesis