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Contribution of the PhoP-PhoQ and PmrA-PmrB two-component regulatory systems to Mg2+-induced gene regulation in Pseudomonas aeruginosa.

Journal of bacteriology - 1 Jun 2006

McPhee Joseph B, Bains Manjeet, Winsor Geoff, Lewenza Shawn, Kwasnicka Agnieszka, Brazas Michelle D, Brinkman Fiona S L, Hancock R E W

Abstract excerpt

When grown in divalent cation-limited medium, Pseudomonas aeruginosa becomes resistant to cationic antimicrobial peptides and polymyxin B. This resistance is regulated by the PhoP-PhoQ and PmrA-PmrB two-component regulatory systems. To further characterize Mg(2+) regulation in P. aeruginosa, microarray transcriptional profiling was conducted to compare wild-type P. aeruginosa grown under Mg(2+)-limited and...

Topics

Bacterial Proteins
Base Sequence
DNA Primers
Gene Expression Regulation, Bacterial
Genotype
Kinetics
Magnesium
Oligonucleotide Array Sequence Analysis
Pseudomonas aeruginosa
Transcription Factors

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Identifiers

PMID: 16707691
DOI: 10.1128/JB.00053-06
PMCID: PMC1482896

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Contribution of the PhoP-PhoQ and PmrA-PmrB two-component regulatory systems to Mg2+-induced gene regulation in Pseudomonas aeruginosa.PMID 16707691Read ↗

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