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Article

Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway.

Cancer research - 1 Jan 1996

Liu Y, Martindale J L, Gorospe M, Holbrook N J

Abstract excerpt

p21WAF1/CIP1 is a cyclin-dependent kinase inhibitor whose expression in mammalian tissues is highly induced in response to stress as well as during normal development and differentiation. Induction of p21WAF1/CIP1 in response to DNA damage occurs through a transcriptional mechanism that is dependent on the activation of the tumor suppressor protein p53. Recent evidence indicates that p21WAF1/CIP1 can also be...

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PMID: 8548769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway.PMID 8548769Read ↗

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