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Cancer therapy and p53

1 Nov 1995

Abstract excerpt

Apoptosis is now recognized as an important process in tissue homeostasis. In malignancy, mutations in apoptotic programs may promote tumor progression as well as reduce the efficacy of cancer therapy. Recent studies identify the product of the p53 tumor-suppressor gene as an important regulator of apoptosis in tumor cells. At the same time, clinical studies implicate p53 mutations in pleiotropic resistance to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 8547404
DOI: 10.1097/00001622-199511000-00013

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Source receipt: pubmed, retrieved 7 Sept 2026.

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