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Article

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

Genes & development - 15 Dec 1995

Schonemann M D, Ryan A K, McEvilly R J, O'Connell S M, Arias C A, Kalla K A, Li P, Sawchenko P E, Rosenfeld M G

Abstract excerpt

Neurons comprising the endocrine hypothalamus are disposed in several nuclei that develop in tandem with their ultimate target the pituitary gland, and arise from a primordium in which three related class III POU domain factors, Brn-2, Brn-4, and Brn-1, are initially coexpressed. Subsequently, these factors exhibit stratified patterns of ontogenic expression, correlating with the appearance of distinct...

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PMID: 8543156
DOI: 10.1101/gad.9.24.3122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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