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Article

Using loss of heterozygosity data in affected pedigree member linkage tests.

Genetic epidemiology - 1 Jan 1995

Lustbader E d, Rebbeck T R, Buetow K H

Abstract excerpt

Linkage analysis can be used to test the hypothesis that a marker locus of known location segregates independently from a presumed disease gene. One way to test this hypothesis is to measure the similarity of marker alleles among pairs of relatives affected with the disease. When the disease under consideration is cancer, it is possible to take advantage of the marker alleles in tumors to revise the similarity...

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PMID: 8536951
DOI: 10.1002/gepi.1370120402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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