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Article

Somatic allele loss in genetic linkage analysis of cancer.

Genetic epidemiology - 1 Jan 1994

Rebbeck T R, Lustbader E D, Buetow K H

Abstract excerpt

The ability to detect or reject genetic linkage in studies of human cancer is often diminished because multiple affected relatives in a pedigree are unavailable for analysis. The observation of somatic allele loss in tumors can provide knowledge about gametic phase. Therefore, consideration of tumor genotype data could be used to obtain knowledge about gametic phase ordinarily gained from a larger sample of...

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PMID: 7835688
DOI: 10.1002/gepi.1370110504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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