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The C. elegans sex-determining gene fem-2 encodes a putative protein phosphatase.

Molecular biology of the cell - 1 Sept 1995

Pilgrim D, McGregor A, Jäckle P, Johnson T, Hansen D

Abstract excerpt

The genetic and molecular analysis of genes involved in the regulation of sex determination in Caenorhabditis elegans suggests that the gene fem-2 plays an important role in regulating a pathway transducing a non-cell-autonomous signal to a nuclear transcription factor. The wild-type fem-2 gene w...

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Molecular Sequence Data
Base Sequence
Alleles
Amino Acid Sequence
Polymerase Chain Reaction
Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA, Complementary

Phosphorylation

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Identifiers

PMID: 8534913
DOI: 10.1091/mbc.6.9.1159
PMCID: PMC301274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8534913-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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The C. elegans sex-determining gene fem-2 encodes a putative protein phosphatase.PMID 8534913Read ↗

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.Semantic proximity Read ↗

Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.Semantic proximity Read ↗

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The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development.Semantic proximity Read ↗

The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions.Semantic proximity Read ↗

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