Article
The C. elegans gon-2 gene encodes a putative TRP cation channel protein required for mitotic cell cycle progression.
Gene - 21 Mar 2001
West R J, Sun A Y, Church D L, Lambie E J
Abstract excerpt
The C. elegans gon-2 gene is required for the post-embryonic mitotic cell divisions of the gonadal precursor cells. A single major transcript of approximately 6.7 kb is derived from the gon-2 locus. This mRNA encodes a protein related to the TRP family of cation channels and has a high degree of similarity to several vertebrate genes, including melastatin. Mutant alleles of gon-2 affect evolutionarily conserved...
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