Article
The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions.
Cell - 23 Mar 1990
Spence A M, Coulson A, Hodgkin J
Abstract excerpt
We report the cloning and sequencing of fem-1, a gene required for sex determination in both germline and somatic tissues in the nematode C. elegans. Clones carrying a 5.5 kb fragment are able to rescue the progeny of a fem-1 mutant when injected into its oocytes. The major fem-1 transcript in bo...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis
- Cell Communication
- Cell Cycle
- Cell Cycle Proteins
- Chromosome Mapping
- Cloning, Molecular
- Female
- Gene Rearrangement
- Intercellular Junctions
- Introns
- Male
- Molecular Sequence Data
- Mutation
- Polymorphism, Genetic