Article
A predicted membrane protein, TRA-2A, directs hermaphrodite development in Caenorhabditis elegans.
Development (Cambridge, England) - 1 Sept 1995
Kuwabara P E, Kimble J
Abstract excerpt
The nematode C. elegans naturally develops as either an XO male or XX hermaphrodite. The sex-determining gene, tra-2, promotes hermaphrodite development in XX animals. This gene encodes a predicted membrane protein, named TRA-2A, which has been proposed to provide the primary feminising activity of the tra-2 locus. Here, we show that transgenic TRA-2A driven from a heat shock promoter can fully feminise the...
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