Article
Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding beta-oxidation enzymes: cross talk between peroxisome proliferator and T3 signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 1995
Chu R, Madison L D, Lin Y, Kopp P, Rao M S, Jameson J L, Reddy J K
Abstract excerpt
Peroxisome proliferators cause rapid and coordinated transcriptional activation of genes encoding peroxisomal beta-oxidation system enzymes by activating peroxisome proliferator-activated receptor (PPAR) isoform(s). Since the thyroid hormone (T3; 3,3',5-triiodothyronine) receptor (TR), another member of the nuclear hormone receptor superfamily, regulates a subset of fatty acid metabolism genes shared with PPAR,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.